The Role of Mitochondria and mit-DNA in Oncogenesis

Mit-DNA is mainly responsible for cell respiration in biological systems, and the genetic alteration of mit-DNA affects mitochondrial activity. It will be here analyzed a well defined mitochondrial cytopathy which is connected, from the moment of birth, with several inherited diseases, such as cancer. The chance to investigate, indirectly and through bed-side evaluation, mitochondria functionality opens new ways to understand and face the very beginning states of the process of oncogenesis, giving original impulses to diagnosis and prevention. Finally, a multidisciplinary and integrated approach involving biology, physics, mathematics, chemistry, philosophy, etc. opens new perspectives both for classical and social sciences.